PROTEIN SYNTHESIS ESSAY | Life Science Grade 12

PROTEIN SYNTHESIS ESSAY
Describe different stages of protein synthesis and mutations that lead to formation of a wrong protein
Transcription
❖ The double helix DNA molecule unwinds/Unzips
❖ When weak hydrogen bonds break
❖ Two separate single strands are formed
❖ One strand is used as a template
❖ To form mRNA
❖ Using free nucleotides from nucleoplasm
❖ He coded message for protein is thus copied into mRNA
❖ mRNA moves through nuclear pores to cytoplasm and attaches to ribosomes Translation
❖ tRNA contains of specific amino acids
❖ When the anticodon on tRNA
❖ Matches the codons on mRNA
❖ tRNA brings specific amino acids to ribosomes
❖ Amino acids become attached by peptide bonds
❖ To form required protein
Mutations
❖ Errors that may occur during DNA replication
❖ Point mutation: replace of one base of codon with another
❖ Resulting in the formation of a wrong protein
❖ Frame shift mutations: addition/deletion of one or more bases on codons
❖ Resulting in change of sequence of all bases on codons
❖ Which results in the formation of a different protein with different function


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